For many patients living with the relentless pain and debilitating symptoms of rheumatoid arthritis (RA), the quest for effective treatment can be an enduring battle. In the past few decades, the landscape of RA management has dramatically shifted with the introduction of biologic therapies.
Infusion therapy is one of the most notable delivery methods for these important medications. Let’s explore how infusion therapies like Stelara, Infliximab, and Renflexis are revolutionizing the care for RA patients.
Understanding Rheumatoid Arthritis and Its Impact
RA is a chronic autoimmune disorder where the body’s immune system mistakenly attacks the joints, resulting in inflammation, pain, and eventually, joint damage and deformities. It is a painful reality for an estimated 1.5 million Americans.
The condition is not only physically excruciating but also emotionally taxing, often causing long-term disability and significantly decreasing the quality of life.
Traditional treatment methods included:
- Non-steroidal anti-inflammatory drugs (NSAIDs)
- Corticosteroids
- Disease-modifying anti-rheumatic drugs (DMARDs) such as methotrexate
While these have been effective for many patients, many patients experience either a lack of response or intolerance to these treatments.
The Role of Biologic and Biosimilar Infusions in RA Treatment
The advent of biologic drugs, designed to either reduce inflammation or target the immune response, signified a critical breakthrough in RA care. Unlike traditional DMARDs, which tend to be less selective in their approach, biologics are engineered to act against specific molecular pathways.
Infusion therapy, where medications are delivered intravenously in a certified infusion center, has paved the way for more controlled and powerful administration of these drugs. The most commonly used infusions for RA include Stelara, Infliximab, and Renflexis, each offering a unique mechanism of action and benefits for patients.
Stelara (Ustekinumab)
Stelara is a newer addition to biologics for RA and is a monoclonal antibody that targets the IL-12 and IL-23 pathways. It disrupts the immune signaling responsible for chronic inflammation.
What’s unique about Stelara is its safety profile compared to some older biologics and its potential to benefit patients who have not responded to other treatments, making it an exciting option for RA patients with complicated treatment histories.
Infliximab (Remicade) and Renflexis (Biosimilar)
First in the class of TNF-alpha inhibitors, Infliximab (known by the brand name Remicade) has been around for several years. It is an essential drug in the management of RA, especially for patients with severe, active disease.
Renflexis, a biosimilar to Remicade, offers a more cost-effective alternative without sacrificing therapeutic efficacy. TNF-alpha inhibitors work by binding and preventing the action of TNF-alpha, a pro-inflammatory cytokine significantly elevated in RA patients.
How Infusion Therapy for RA Works?
The beauty of infusion therapy lies in its ability to provide a reliable, systemic impact with known and consistent dosing. The medications given through infusion are designed to weaken specific overactive parts of the immune system in RA patients, helping to reduce symptoms and prevent further joint damage.
For example, IL-12 and IL-23 are key cytokines that modulate inflammation, especially in autoimmune diseases. Stelara’s ability to block these can lead to a significant reduction in the signs and symptoms of RA.
TNF-alpha inhibitors like Infliximab and its biosimilar Renflexis have an immediate and potent anti-inflammatory response that can provide rapid relief to patients.
What does an Infusion Therapy Process for RA Involve?
A typical infusion therapy session for RA involves the following steps:
- Preparation: Before starting the infusion therapy for rheumatoid arthritis, your healthcare provider will likely conduct a physical examination and review your medical history to ensure you’re in good health for the procedure.
- Administration: The medication is administered through an intravenous (IV) line inserted into a vein, usually in your arm. The duration of this process can vary from a few minutes to four hours, depending on the specific RA medication and your individual treatment plan.
- Monitoring: During the infusion, medical staff will monitor you for any adverse reactions. This might include checking your blood pressure, heart rate, and temperature at regular intervals.
- Post-Infusion Observation: After the infusion is complete, you might be observed for a period to ensure no late-onset reactions occur.
Infusion Therapy for Rheumatoid Arthritis Near Me
Infusion therapy with biologic drugs presents a critical development in the treatment of rheumatoid arthritis. Its targeted and potent action provides hope and a better quality of life for many patients.
At GI Care Infusions, we have a team of highly trained and exceptionally skilled providers who offer infusion therapy to treat a wide range of immune system conditions, including rheumatoid arthritis. In addition to offering infusion therapy for rheumatoid arthritis treatment, we also recommend physical therapy and occupational therapy so that you can live a happier and more fulfilled life.
For more information about infusion therapy for rheumatoid arthritis or to schedule a consultation, call our infusion center today at (470) 785-4616 or fill out our online appointment request form. We look forward to serving you!
